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Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of multiple active ingredient, which may make them more efficient and safer. Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular is the fact that by right now there aren't any long term prescription weightloss pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug can also raise blood pressure and pulse rate, and must not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must not be used in patients with uncontrolled high blood pressure level, in addition to by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. 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Post-acute alcohol withdrawal symptoms (PAWS) can be managed promptly and effectively, which further improves comfort and reduces relapse rates; this contrasts sharply with inpatient facilities, where patients have been completely discharged before post-acute withdrawal symptoms develop, leaving them no recourse with how to effectively and safely deal with them.